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Dompen-10 Tablet
 Key Product >>Dompen-10 Tablet

Dompen-10 Tablet
Domperidone BP 10 mg: Each film coated white, circular tablet contains Domperidone Maleate BP equivalent to 10 mg Domperidone.

INDICATION
1. Stimulation of gut mobility
a) Non-ulcer dyspepsia
b) Esophageal reflux, reflux esophagitis and gastritis
c) Diabetic gastroparesis
d) Functional dyspepsia
e) Speeding barium transit 'follow-through' radiological studies.
2. Prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radio therapy and anti-parkinsonism therapy.
3. In the symptomatic treatment of migraine.

Dosage and Administration:
The recommended oral dose for
Adults : 10-20 mg every 4-8 hours daily
Children : 0.2-0.4 mg/kg every 4-8 hours daily.
Note: Dompen-10 Tablet should be taken 15-30 minutes before a meal. For acute nausea and vomiting, maximum period of treatment is 12 weeks.

Contra indications:
Dompen-10 is Contraindicated to patients who have know hypersensitivity to this drug and in case of neonates.

Precautions:
Dompen-10 should be used with absolute caution in case of children because there may be an increased risk of extrapyramidal reactions in young children because of an incompletely developed blood-brain barrier.

Side effects:
Dompen-10 may produce hyperprolactinemia (1.3% frequency). This may result in galactorrhea, breast enlargement and soreness and reduced libido. Dry mouth (1.9%, thirst, headache (1.2%) nervousness, drowsiness (0.4%), diarrhoea (0.2%), skin rash and itching (0.1%) may occur during treatment with Dompen-10. Extra-pyramidal reactions are seen in 0.05% of patients in clinical studies.

Use in Pregnancy & Lactation:
Pregnant women: The safety of Dompen-10 has not been proven and it is therefore not recommended during pregnancy. Animal studies have not demonstrated teratogenic effects on the fetus.
Lactating mother: Dompen-10 may precipitate galactorrhea and improve post-natal lactation. It is secreted in breast milk but in very small quantities insufficient to be considered harmful.

Drug interactions:
Dompen-10 may reduce the hypoprolactinemic effect of bromocriptine. The action of Dompen-10 on GI function may be antagonized by anti-muscarinics and opioid analgesics.

Over dosage:
There are no reported cases of over dosage.

Commercial Pack:
Dompen-10 Tablet : Each box contains 10 blister strips of 10 tablets.