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Din-10
Din-10
DIN-10
 Key Product >>DIN-10

DIN-10 Tablet
Loratadine INN

Din-10
(Loratadine INN) is a preparation of loratadine. Loratadine is a long acting tricyclic antihistamine with selective peripheral H1 receptor antagonistic activity and no central sedative or anticholinergic effect.

Indications: Din-10 provides fast effective relief from the symptoms of hay fever, allergic rhinitis such as sneezing. nasal discharge, itching, ocular itching and burning. Nasal and ocular signs and symptoms are relieved rapidly after oral administration. Din-10 is also indicated for the felief of the symptoms associated with idiopathic chronic urticaria. In children over 2 years Din-10 is indicated for the symptomatic relief of seasonal allergic rhinitis and allergic skin conditions such as urticaria, nettle-rash.

Dosage and administration: Tablet : Adults and children over 12 years of age: One Din-10 mg tablet, once a day when symptoms required treatment.
Children 2-12 years : (Body weight more than 30 kg) 10 mg Din-10 tablet once daily.
Below 2 years of a age : Safety and efficacy of Din-10 (loratadine) has not been established.

Contra indications: Loratadine is contraindicated in patients who have shown hypersensitivity or idiosyncrasy to their components.

Use in pregnancy and lactation:
There is no experience of the use of loratadine in human pregnancy, hence it should not be used during pregnancy. Loratadine is excreted in breast milk, so it should not be administered to lactating mother.

Side-effects:
During controlled clinical studies the incidence of adverse events including sedation and anticholinergic effects observed with 10 mg loratadine was comparable to that observed with placebo. Fatigue, nausea and headache were reported rarely. Scientific studies show that loratadine dose not cause drowsiness. It does not affect performance and ability to drive or tasks requiring concentration.

Drug interactions:
When administered concurrently with alcohol, loratadine has no potentiating effects as measured by psychomotor performance studies. Interactions with other drugs have not been reported.

Overdosage:
In the event of overdose, treatment which should be started immediately is symptomatic and supportive. The patients should be induced to vomit, even if emesis has occurred spontaneously, but not in the patients with impaired consciousness. Administration of activated charcoal as a slurry with water may be attempted following emesis. If vomiting is unsuccessful or contraindicated, gastric lavage should be performed.

Pharmaceutical precaution:
Store in a cool, dry place and protect from light. Keep out of reach of children.

Packaging:
Din-10 tablet:Box containing 10 blister strips of 10 tablets each. Each tablet contains loratadine INN 10 mg.